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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DEPDC5
All Species:
13.33
Human Site:
S1033
Identified Species:
32.59
UniProt:
O75140
Number Species:
9
Phosphosite Substitution
Charge Score:
0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75140
NP_001007189.1
1572
177910
S1033
K
K
G
T
S
A
L
S
A
L
L
E
M
E
A
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_852875
773
87442
D253
H
K
G
R
Y
Y
E
D
F
Y
K
V
V
V
Q
Cat
Felis silvestris
Mouse
Mus musculus
P61460
1527
173129
S990
K
K
G
T
S
A
L
S
A
L
L
E
M
E
A
Rat
Rattus norvegicus
NP_001100699
1456
164725
Q935
Q
K
S
L
G
E
Q
Q
T
S
V
H
G
K
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517877
828
93963
E308
S
A
Q
G
N
Y
L
E
A
I
N
L
S
F
N
Chicken
Gallus gallus
XP_415249
1571
177723
S1033
K
K
G
T
S
A
L
S
A
L
L
E
M
E
A
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_691450
1590
178752
S1034
K
K
G
T
S
A
L
S
A
L
L
E
L
E
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_728620
1472
168864
N952
F
P
D
V
T
A
D
N
T
R
E
Q
V
E
D
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_794020
1608
181354
P1048
I
A
G
D
L
T
H
P
G
S
R
S
S
P
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Q7S9J6
2004
222187
F1208
L
R
F
W
R
A
R
F
V
L
I
P
M
T
A
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
48
N.A.
91.7
87.4
N.A.
49.5
89.1
N.A.
75.5
N.A.
35.7
N.A.
N.A.
32.4
Protein Similarity:
100
N.A.
N.A.
48.6
N.A.
93.8
89.6
N.A.
50.9
94
N.A.
84.5
N.A.
53.7
N.A.
N.A.
48.6
P-Site Identity:
100
N.A.
N.A.
13.3
N.A.
100
6.6
N.A.
13.3
100
N.A.
86.6
N.A.
13.3
N.A.
N.A.
6.6
P-Site Similarity:
100
N.A.
N.A.
20
N.A.
100
33.3
N.A.
26.6
100
N.A.
93.3
N.A.
40
N.A.
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
20
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
35.7
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
26.6
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
40
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
20
0
0
0
60
0
0
50
0
0
0
0
0
40
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
10
10
0
0
10
10
0
0
0
0
0
0
10
% D
% Glu:
0
0
0
0
0
10
10
10
0
0
10
40
0
50
0
% E
% Phe:
10
0
10
0
0
0
0
10
10
0
0
0
0
10
0
% F
% Gly:
0
0
60
10
10
0
0
0
10
0
0
0
10
0
0
% G
% His:
10
0
0
0
0
0
10
0
0
0
0
10
0
0
0
% H
% Ile:
10
0
0
0
0
0
0
0
0
10
10
0
0
0
0
% I
% Lys:
40
60
0
0
0
0
0
0
0
0
10
0
0
10
0
% K
% Leu:
10
0
0
10
10
0
50
0
0
50
40
10
10
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
40
0
0
% M
% Asn:
0
0
0
0
10
0
0
10
0
0
10
0
0
0
10
% N
% Pro:
0
10
0
0
0
0
0
10
0
0
0
10
0
10
0
% P
% Gln:
10
0
10
0
0
0
10
10
0
0
0
10
0
0
20
% Q
% Arg:
0
10
0
10
10
0
10
0
0
10
10
0
0
0
0
% R
% Ser:
10
0
10
0
40
0
0
40
0
20
0
10
20
0
10
% S
% Thr:
0
0
0
40
10
10
0
0
20
0
0
0
0
10
0
% T
% Val:
0
0
0
10
0
0
0
0
10
0
10
10
20
10
10
% V
% Trp:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
10
20
0
0
0
10
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _